According to the Catalan health service, 893 people received medical attention as a result of injuries sustained during clashes with police.
Four of those people were seriously injured but stable.
The staggering figure is more than double the amount of civilians and police injured in the 2010 and 2011 protests in Greece combined.
Both anti-austerity protests happened over several months and saw around 400 injuries.
Meanwhile, Catalan leader Carles Puigedemont has said 90% of Sunday’s vote favours independence, and has promised official results within a few days.