The Premier League side are understood to be jetting out to the Costa del Sol this Saturday, immediately after their match with Southampton.
The 45-year-old Portuguese is understood to be looking to refresh his team with some southern sunshine ahead of a renewed European qualification push.
The Midlands club lost the chance to qualify for the Europa League via the FA Cup after losing to Watford 3-2 in a thrilling semi final on Sunday.
But Santo and his players are still in with a chance of sealing a place in the European tournament for next season if they can finish seventh in the Premier League.
They currently lie eighth in the table, tied on 47 points with Leicester City, who are in seventh, though with a better goal difference.
It is not the first time that Wolves have made the journey to the exclusive playground of the rich and famous on Spain’s Costa del Sol.
They were spotted in Marbella, dining at La Sala, back in February, following a shocking 2-0 home defeat at Molineux to Nottingham Forest.
It came after other Premier League sides, including Liverpool and West Ham were also spotted sunning themselves in Spain in January.
- Andy Murray’s Spanish doubles partner named in Wimbledon match-fixing investigation by police - 20 Jun, 2019 @ 09:46
- Death of British teen in Spain who was third to die at same apartment block ‘could have been prevented’ - 19 Jun, 2019 @ 13:38
- OH MY GOGH: Gun Van Gogh ‘killed himself with’ to be auctioned off while southern Spain tour of his work continues - 19 Jun, 2019 @ 12:30
- CASTING CALL: Netflix needs male and female extras in Spain’s Andalucia for new drama series - 19 Jun, 2019 @ 10:57
- POSH: Brits Victoria and David Beckham jet into Spain’s Andalucia for celeb wedding of year catered for by Dani Garcia - 18 Jun, 2019 @ 16:54
- WATCH: Shocking moment bullring volunteer in Spain gored to death in front of 2,000 fans as bull ran back into pen - 18 Jun, 2019 @ 12:52
- Facial recognition cameras installed at Gibraltar Airport - 18 Jun, 2019 @ 11:00
- UK Government denies issuing ‘fresh warning’ of terror threat in Spain - 17 Jun, 2019 @ 17:34
- UK primary school hires convicted CHILD KILLER from Spain’s Andalucia who stabbed schoolgirl victim 32 times - 17 Jun, 2019 @ 13:44
- REVEALED: These countries made the most asylum applications to Spain so far this year - 17 Jun, 2019 @ 11:20